Formic Acid

Formic Acid

SCHEMBL29617066

O=C1CCC(N2C(=O)c3ccc(OCCN4CCNCC4)cc3C2=O)C(=O)N1.O=CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 15/20 0.53
IRAK4 Q9NWZ3 2/20 0.51
DDB1 Q16531 10/20 0.51
ALDH1A1 P00352 1/20 0.49
CHRM2 P08172 1/20 0.49
OPRM1 P35372 1/20 0.49
IKZF3 Q9UKT9 1/20 0.49
CYP1A2 P05177 1/20 0.49
TSHR P16473 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
LRRK2 Q5S007 1/20 0.47
EGFR P00533 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL23705607 1.00 CRBN (0.53) CRBNIRAK4DDB1ALDH1A1CHRM2
Formic Acid SCHEMBL30058723 0.96 CRBN (0.52) CRBNIRAK4DDB1ALDH1A1CHRM2
Formic Acid SCHEMBL23705587 0.96 CRBN (0.52) CRBNIRAK4DDB1ALDH1A1CHRM2
SCHEMBL23705600 0.95 CRBN (0.56) CRBNIRAK4DDB1ALDH1A1CHRM2
SCHEMBL23729483 0.91 CRBN (0.54) CRBNIRAK4DDB1ALDH1A1CHRM2
Formic Acid SCHEMBL23705562 0.91 CRBN (0.53) CRBNIRAK4DDB1ALDH1A1CHRM2
SCHEMBL30432431 0.90 CRBN (0.53) CRBNIRAK4DDB1ALDH1A1CHRM2
SCHEMBL20128892 0.90 IRAK4 (0.52) CRBNIRAK4DDB1ALDH1A1CHRM2
SCHEMBL20128895 0.89 IRAK4 (0.54) CRBNIRAK4DDB1ALDH1A1CHRM2
SCHEMBL23705491 0.86 CRBN (0.59) CRBNIRAK4DDB1ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335373-B Compounds and uses thereof 福宏治疗公司 2025-05-20 CN disclosed
CN-116867785-A Compounds and uses thereof 福宏治疗公司 2023-10-10 CN disclosed
EP-4097096-A2 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2022-12-07 EP disclosed
CN-115335373-A Compound and use thereof 福宏治疗公司 2022-11-11 CN disclosed
WO-2022109396-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2022-05-27 WO disclosed