Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | FLT1 | P17948 | 2/20 | 0.54 |
| ▸ | FLT4 | P35916 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | GIGYF2 | Q6Y7W6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617191 | 0.89 | PKM (0.64) | PKMFLT1FLT4KDRPRSS1 | |
| SCHEMBL17171624 | 0.82 | PKM (0.68) | PKMFLT1FLT4KDRPRSS1 | |
| SCHEMBL24398126 | 0.82 | PKM (0.44) | PKMFLT1FLT4KDRPRSS1 | |
| SCHEMBL19017236 | 0.80 | F2 (0.73) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15216220 | 0.80 | F2 (0.73) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19751698 | 0.80 | F2 (0.73) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL4968230 | 0.80 | F2 (0.73) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL22420486 | 0.79 | F2 (0.68) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL30574542 | 0.79 | TDP1 (0.71) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL13328289 | 0.79 | PKM (0.69) | PKMPRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270253-A1 | SITE-SELECTIVE MODIFICATION OF PROTEINS | UNIVERSITY OF COPENHAGEN (DK) | 2025-08-28 | — | — | US | disclosed |
| EP-4237856-A1 | SITE-SELECTIVE MODIFICATION OF PROTEINS | Danmarks Tekniske Universitet (DK) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090520-A1 | SITE-SELECTIVE MODIFICATION OF PROTEINS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2022-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270253-A1 | SITE-SELECTIVE MODIFICATION OF PROTEINS | PTMS, DNPEP, AADAC | PKM 1991/4885FLT1 3153/4885FLT4 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.