Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672847 | 1.00 | PNMT (0.49) | PNMTNPC1RAB9AEGFRHTR2B | |
| SCHEMBL6675580 | 0.89 | PNMT (0.49) | PNMTNPC1RAB9AEGFRHTR2B | |
| SCHEMBL6557930 | 0.87 | PNMT (0.47) | PNMTNPC1RAB9AEGFRHTR2B | |
| SCHEMBL7166662 | 0.85 | PNMT (0.46) | PNMTNPC1RAB9AEGFRHTR2B | |
| SCHEMBL2231457 | 0.85 | NPC1 (0.47) | PNMTNPC1RAB9AEGFRHTR2B | |
| Hydrochloric Acid SCHEMBL6558717 | 0.85 | PNMT (0.46) | PNMTNPC1RAB9AEGFRHTR2B | |
| Hydrochloric Acid SCHEMBL6558708 | 0.85 | PNMT (0.46) | PNMTNPC1RAB9AEGFRHTR2B | |
| SCHEMBL19682347 | 0.85 | PNMT (0.46) | PNMTNPC1RAB9AEGFRHTR2B | |
| SCHEMBL1609628 | 0.85 | PNMT (0.46) | PNMTNPC1RAB9AEGFRHTR2B | |
| SCHEMBL1567173 | 0.85 | NPC1 (0.47) | PNMTNPC1RAB9AEGFRHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994144-A1 | A NEW PROCESS FOR SYNTHESIZING C2 BRIDGED CYCLOPENTADIENYL LIGANDS AND CORRESPONDING ANSA-METALLOCENE CATALYSTS | Haldia Petrochemicals Limited (IN) | 2022-05-11 | — | — | EP | disclosed |