Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | CA2 | P00918 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA3 | P07451 | 4/20 | 0.53 |
| ▸ | CA4 | P22748 | 4/20 | 0.53 |
| ▸ | CA6 | P23280 | 4/20 | 0.53 |
| ▸ | CA5A | P35218 | 4/20 | 0.53 |
| ▸ | CA7 | P43166 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843062 | 0.89 | SMN1; SMN2 (0.74) | SMN1; SMN2CA2KMT2AMEN1CA1 | |
| SCHEMBL6359372 | 0.87 | SMN1; SMN2 (0.72) | SMN1; SMN2CA2KMT2AMEN1NAAA | |
| SCHEMBL25738470 | 0.87 | KMT2A (0.55) | SMN1; SMN2CA2KMT2AKDM4EMEN1 | |
| SCHEMBL25738414 | 0.84 | KMT2A (0.57) | SMN1; SMN2CA2KMT2AKDM4EMEN1 | |
| SCHEMBL3127370 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2CA2KMT2AMEN1NAAA | |
| SCHEMBL16117373 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2ANAAAL3MBTL1ALDH1A1 | |
| SCHEMBL3047715 | 0.81 | CA2 (0.50) | SMN1; SMN2CA2KMT2AKDM4EMEN1 | |
| SCHEMBL14526568 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2CA2KMT2AMEN1NAAA | |
| SCHEMBL2972657 | 0.80 | SMN1; SMN2 (0.84) | SMN1; SMN2KMT2ANAAAL3MBTL1ALDH1A1 | |
| SCHEMBL6258472 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2KDM4ENAAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312682-B2 | Selective inhibitors of carbonic anhydrase | VILNIUS UNIVERSITY (LT) | 2022-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312682-B2 | Selective inhibitors of carbonic anhydrase | CA2, CA9, CA7 | SMN1; SMN2 1397/4885CA2 1/4885KMT2A 2952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.