Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 18/20 | 1.00 |
| ▸ | DRD2 | P14416 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | APAF1 | O14727 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | F3 | P13726 | 6/20 | 0.87 |
| ▸ | DRD3 | P35462 | 6/20 | 0.81 |
| ▸ | DRD5 | P21918 | 3/20 | 0.81 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.81 |
| ▸ | DRD4 | P21917 | 2/20 | 0.81 |
| ▸ | HTR1A | P08908 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Scoulerine SCHEMBL679505 | 1.00 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 | |
| Discretamine SCHEMBL13885928 | 1.00 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 | |
| Discretamine SCHEMBL29362664 | 1.00 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 | |
| Scoulerine SCHEMBL29462969 | 1.00 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 | |
| Discretamine SCHEMBL4202179 | 0.99 | DRD1 (0.98) | DRD1DRD2KDM4ELMNACYP1A2 | |
| Tetrahydropalmatrubine SCHEMBL20759895 | 0.93 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 | |
| Tetrahydropalmatrubine SCHEMBL12904352 | 0.93 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 | |
| SCHEMBL680031 | 0.90 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 | |
| SCHEMBL29561422 | 0.90 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 | |
| SCHEMBL14703846 | 0.90 | DRD1 (1.00) | DRD1DRD2KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606829-A | Rhizoma corydalis-derived oxymethyl transferase CyS2OMT and functions thereof | 中国中医科学院中药研究所 | 2023-08-18 | — | — | CN | claimed |
| CN-115896058-B | O-methyltransferase protein with high specific catalytic function on various BIAS parent nuclei, and encoding gene and application thereof | 中国中医科学院中药研究所 | 2023-07-14 | — | — | CN | claimed |
| CN-119709674-B | Berberine bridge enzyme mutant and application thereof in synthesis of (S) -scolerine | 江南大学 | 2026-04-17 | — | — | CN | disclosed |
| CN-119709674-A | Berberine bridge enzyme mutant and application thereof in synthesis of (S) -scolerine | 江南大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119709674-A | Berberine bridge enzyme mutant and application thereof in synthesis of (S) -scolerine | 江南大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119661514-A | Herba corydalis Bungeanae total alkaloid extract for preventing and treating hyperuricemia, and preparation method and application thereof | 云南中医药大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-116964190-A | Method for increasing yields of morphinan alkaloids and derivatives | 安思雅公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-4247937-A1 | METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES | Antheia, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116606829-A | Rhizoma corydalis-derived oxymethyl transferase CyS2OMT and functions thereof | 中国中医科学院中药研究所 | 2023-08-18 | — | — | CN | disclosed |
| CN-115896058-B | O-methyltransferase protein with high specific catalytic function on various BIAS parent nuclei, and encoding gene and application thereof | 中国中医科学院中药研究所 | 2023-07-14 | — | — | CN | disclosed |
| CN-115896058-A | O-methyltransferase protein with high specific catalytic function on multiple BIAS mother nuclei and coding gene and application thereof | 中国中医科学院中药研究所 | 2023-04-04 | — | — | CN | disclosed |
| WO-2022109194-A1 | METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES | ANTHEIA, INC. (US) | 2022-05-27 | — | — | WO | disclosed |