Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087755 | 0.96 | KDM4E (0.43) | OPRL1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29617620 | 0.96 | KDM4E (0.43) | OPRL1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29087798 | 0.92 | CHRM2 (0.41) | OPRL1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL30646810 | 0.92 | CHRM2 (0.41) | OPRL1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29087709 | 0.91 | PRKAA2 (0.48) | KCNH2POLBMAPTCACNA1G | |
| SCHEMBL29617624 | 0.91 | PRKAA2 (0.48) | KCNH2POLBMAPTCACNA1G | |
| SCHEMBL29617597 | 0.88 | CHRM2 (0.39) | OPRL1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL30646794 | 0.87 | PSEN1 (0.48) | OPRL1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29087732 | 0.87 | PSEN1 (0.48) | OPRL1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29087735 | 0.87 | PSEN1 (0.48) | OPRL1CHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247374-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | Telo Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |