Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087755 | 1.00 | KDM4E (0.43) | KDM4ECHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29617612 | 0.96 | GPBAR1 (0.41) | KDM4ECHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL30646810 | 0.96 | CHRM2 (0.41) | KDM4ECHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29087798 | 0.96 | CHRM2 (0.41) | KDM4ECHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29087709 | 0.95 | PRKAA2 (0.48) | POLBMAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL29617624 | 0.95 | PRKAA2 (0.48) | POLBMAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL29087783 | 0.92 | USP2 (0.42) | KDM4ECHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29617623 | 0.92 | USP2 (0.42) | KDM4ECHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29617597 | 0.92 | CHRM2 (0.39) | KDM4ECHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL29617632 | 0.91 | DRD2 (0.43) | KDM4ECHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247374-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | Telo Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |