SCHEMBL29618013

SCHEMBL29618013

C[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ NMT2 O60551 1/20 0.42
▸ NMT1 P30419 1/20 0.42
▸ MME P08473 2/20 0.41
▸ GSR P00390 1/20 0.41
▸ GNPAT O15228 1/20 0.41
▸ DPP8 Q6V1X1 1/20 0.41
▸ DPP9 Q86TI2 1/20 0.41
▸ DPP7 Q9UHL4 1/20 0.41
▸ BACE1 P56817 1/20 0.40
▸ FOLH1 Q04609 1/20 0.39
▸ CPB2 Q96IY4 2/20 0.38
▸ TLR2 O60603 1/20 0.38
▸ GNAI3 P08754 1/20 0.38
▸ GNAO1 P09471 1/20 0.38
▸ GNAI1 P63096 1/20 0.38
▸ ENPEP Q07075 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29858382 0.94 GSR (0.46) GSRGNPATDPP8DPP9DPP7
SCHEMBL29592231 0.93 NMT1 (0.46) NMT2NMT1MMEGNPATFOLH1
SCHEMBL30502876 0.93 GSR (0.47) NMT2NMT1MMEGSRGNPAT
SCHEMBL30954896 0.93 GSR (0.47) NMT2NMT1MMEGSRGNPAT
SCHEMBL30502877 0.93 GSR (0.47) NMT2NMT1MMEGSRGNPAT
SCHEMBL30725894 0.93 GSR (0.47) NMT2NMT1MMEGSRGNPAT
SCHEMBL30423473 0.90 GSR (0.47) NMT2NMT1MMEGSRDPP8
SCHEMBL29695384 0.90 GSR (0.47) NMT2NMT1MMEGSRDPP8
SCHEMBL29396993 0.88 GNPAT (0.49) NMT2NMT1MMEGSRGNPAT
SCHEMBL31188429 0.87 GSR (0.47) NMT2NMT1GSRDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220145278-A1 PROTEIN PRODUCTION IN FILAMENTOUS FUNGAL CELLS IN THE ABSENCE OF INDUCING SUBSTRATES DANISCO US INC (US) 2022-05-12 — — US claimed
CN-109790510-B Protein production in filamentous fungal cells in the absence of an inducing substrate 丹尼斯科美国公司 2024-04-12 — — CN disclosed
JP-2023109919-A PROTEIN PRODUCTION IN FILAMENTOUS FUNGAL CELLS IN ABSENCE OF INDUCING SUBSTRATES ダニスコ・ユーエス・インク 2023-08-08 — — JP disclosed
US-20220145278-A1 PROTEIN PRODUCTION IN FILAMENTOUS FUNGAL CELLS IN THE ABSENCE OF INDUCING SUBSTRATES DANISCO US INC (US) 2022-05-12 — — US disclosed
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