SCHEMBL29695384

SCHEMBL29695384

C[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GSR P00390 1/20 0.47
▸ DPP8 Q6V1X1 2/20 0.46
▸ DPP9 Q86TI2 2/20 0.46
▸ DPP7 Q9UHL4 2/20 0.46
▸ GNAI3 P08754 1/20 0.43
▸ GNAO1 P09471 1/20 0.43
▸ GNAI1 P63096 1/20 0.43
▸ NMT2 O60551 1/20 0.42
▸ NMT1 P30419 1/20 0.42
▸ FOLH1 Q04609 1/20 0.41
▸ DPP4 P27487 1/20 0.41
▸ MME P08473 3/20 0.40
▸ CPB2 Q96IY4 4/20 0.40
▸ NOD1 Q9Y239 1/20 0.39
▸ THRB P10828 1/20 0.38
▸ ERAP2 Q6P179 1/20 0.38
▸ ERAP1 Q9NZ08 1/20 0.38
▸ LNPEP Q9UIQ6 1/20 0.38
▸ TGFBR1 P36897 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30423473 1.00 GSR (0.47) GSRDPP8DPP9DPP7GNAI3
SCHEMBL29397210 0.92 GSR (0.50) GSRDPP8DPP9DPP7GNAI3
SCHEMBL1923416 0.91 GSR (0.56) GSRDPP8DPP9DPP7GNAI3
SCHEMBL28264447 0.91 GSR (0.56) GSRDPP8DPP9DPP7GNAI3
SCHEMBL30445302 0.91 NMT1 (0.47) GSRNMT2NMT1FOLH1CPB2
SCHEMBL29618013 0.90 NMT2 (0.42) GSRDPP8DPP9DPP7GNAI3
SCHEMBL31593295 0.89 NMT1 (0.45) DPP8DPP9DPP7NMT2NMT1
SCHEMBL29727679 0.89 FOLH1 (0.50) DPP8DPP9NMT2NMT1FOLH1
SCHEMBL31188429 0.89 GSR (0.47) GSRDPP8DPP9DPP7GNAI3
SCHEMBL30080483 0.89 FOLH1 (0.48) GSRDPP8DPP9DPP7GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12128110-B2 Transglutaminase conjugation method and linker PAUL SCHERRER INSTITUT (CH) 2024-10-29 — — US claimed
US-20230295276-A1 ANTIBODY FOR PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND USES THEREOF NOVASCOPE BIOCHIPS INC. (US) 2023-09-21 — — US claimed
WO-2023178265-A2 ANTIBODY FOR PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND USES THEREOF NOVASCOPE BIOCHIPS INC. (US) 2023-09-21 — — WO claimed
WO-2023094980-A1 ANTIBODIES TO CORONAVIRUS FONDAZIONE TOSCANA LIFE SCIENCES (IT) 2023-06-01 — — WO claimed
US-20250161479-A1 TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER PAUL SCHERRER INSTITUT (CH) 2025-05-22 — — US disclosed
US-20250115661-A1 BROADLY NEUTRALIZING ANTI-HIV ANTIBODIES AND EPITOPE THEREFOR THE ROCKEFELLER UNIVERSITY (US) 2025-04-10 — — US disclosed
US-12128110-B2 Transglutaminase conjugation method and linker PAUL SCHERRER INSTITUT (CH) 2024-10-29 — — US disclosed
US-20240350656-A1 TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER PAUL SCHERRER INSTITUT (CH) 2024-10-24 — — US disclosed
EP-4267193-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF Ludwig-Maximilians-Universität München (DE) 2023-11-01 — — EP disclosed
US-20230295276-A1 ANTIBODY FOR PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND USES THEREOF NOVASCOPE BIOCHIPS INC. (US) 2023-09-21 — — US disclosed
WO-2023178265-A2 ANTIBODY FOR PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS AND USES THEREOF NOVASCOPE BIOCHIPS INC. (US) 2023-09-21 — — WO disclosed
WO-2023094980-A1 ANTIBODIES TO CORONAVIRUS FONDAZIONE TOSCANA LIFE SCIENCES (IT) 2023-06-01 — — WO disclosed
WO-2022136555-A9 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-09-22 — — WO disclosed
WO-2022136555-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161479-A1 TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER TGM3, TGM2, TGM1 GSR 781/4885DPP8 1743/4885DPP9 1565/4885
US-12128110-B2 Transglutaminase conjugation method and linker TGM3, TGM2, TGM1 GSR 716/4885DPP8 2007/4885DPP9 1834/4885
US-20240350656-A1 TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER TGM3, TGM2, TGM1 GSR 710/4885DPP8 1915/4885DPP9 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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