Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 11/20 | 0.88 |
| ▸ | SRC | P12931 | 8/20 | 0.88 |
| ▸ | LCK | P06239 | 4/20 | 0.88 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.88 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.88 |
| ▸ | EGFR | P00533 | 2/20 | 0.88 |
| ▸ | FYN | P06241 | 2/20 | 0.88 |
| ▸ | CSF1R | P07333 | 2/20 | 0.88 |
| ▸ | YES1 | P07947 | 2/20 | 0.88 |
| ▸ | LYN | P07948 | 2/20 | 0.88 |
| ▸ | RET | P07949 | 2/20 | 0.88 |
| ▸ | HCK | P08631 | 2/20 | 0.88 |
| ▸ | KIT | P10721 | 2/20 | 0.88 |
| ▸ | BCR | P11274 | 2/20 | 0.88 |
| ▸ | BRAF | P15056 | 2/20 | 0.88 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.88 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.88 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.88 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.88 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3507589 | 1.00 | ABL1 (0.88) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL29618215 | 0.96 | ABL1 (0.87) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL28935340 | 0.96 | ABL1 (0.87) | ABL1SRCLCKPKMYT1EPHB6 | |
| Dasatinib Anhydrous SCHEMBL8226 | 0.94 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| Dasatinib Anhydrous SCHEMBL29381185 | 0.94 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| Dasatinib Anhydrous SCHEMBL28350326 | 0.94 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL13164781 | 0.94 | ABL1 (0.88) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL31501075 | 0.93 | ABL1 (0.89) | ABL1SRCLCKPKMYT1EPHB6 | |
| Dasatinib Anhydrous SCHEMBL16618598 | 0.93 | ABL1 (1.00) | ABL1SRCLCKPKMYT1EPHB6 | |
| SCHEMBL15984308 | 0.93 | ABL1 (0.89) | ABL1SRCLCKPKMYT1EPHB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357889-B | Protein degradation targeting compound, anti-tumor application thereof, intermediate thereof and application of intermediate | 上海科技大学 | 2022-03-15 | — | — | CN | disclosed |