SCHEMBL29618247

SCHEMBL29618247

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(N)=O)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)O)C(C)C)[C@@H](C)CC

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 7/20 0.50
VIPR2 P41587 5/20 0.49
VIPR1 P32241 4/20 0.47
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
CTSD P07339 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30512547 0.90 BACE1 (0.51) BACE1VIPR2VIPR1GRIN2DGRIN3B
SCHEMBL31346757 0.89 BACE1 (0.55) BACE1VIPR2VIPR1GRIN2DGRIN3B
SCHEMBL30512610 0.89 BACE1 (0.55) BACE1VIPR2VIPR1GRIN2DGRIN3B
SCHEMBL10700927 0.89 BACE1 (0.49) BACE1CTSD
SCHEMBL10700917 0.89 BACE1 (0.49) BACE1CTSD
SCHEMBL30182817 0.88 BACE1 (0.58) BACE1VIPR2VIPR1GRIN2DGRIN3B
SCHEMBL31614422 0.87 BACE1 (0.52) BACE1VIPR2VIPR1GRIN2DGRIN3B
SCHEMBL30512778 0.87 GRIN2D (0.56) BACE1VIPR2VIPR1GRIN2DGRIN3B
SCHEMBL29679673 0.87 GRIN2D (0.51) VIPR2VIPR1GRIN2DGRIN3BGRIN1
SCHEMBL29453346 0.87 BACE1 (0.56) BACE1VIPR2VIPR1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250177373-A1 COMPOSITIONS AND METHODS FOR TARGETING A VIRAL INFECTION THE CHILDEREN'S MEDICAL CENTER CORPORATION (US) 2025-06-05 US disclosed
EP-4554628-A1 HIV IMMUNOGENIC POLYPEPTIDES AND VACCINES AND USES THEREOF GILEAD SCIENCES, INC. (US) 2025-05-21 EP disclosed
CN-115010805-B HIV-1 GP41 neutralizing antibodies and uses thereof 美国政府(由卫生和人类服务部的部长所代表) 2025-01-28 CN disclosed
US-20240366738-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE AGILENT TECHNOLOGIES INC (US) 2024-11-07 US disclosed
WO-2024220982-A1 COMPOSITIONS COMPRISING APTAMERS AND METHODS OF MODULATING THE IMMUNE RESPONSE USING THE SAME THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2024-10-24 WO disclosed
US-12064425-B2 Compositions and methods for targeting a viral infection THE CHILDREN'S MEDICAL CENTER CORPORATION 2024-08-20 US disclosed
CN-114478796-B Modified human immunodeficiency virus membrane proteins and uses thereof 厦门大学 2024-08-06 CN disclosed
US-11992518-B2 Molecular vaccines for infectious disease AGILENT TECHNOLOGIES, INC. (US) 2024-05-28 US disclosed
CN-111108116-B Retroviral vectors 牛津遗传学有限公司 2024-03-26 CN disclosed
CN-110087679-B Virus-like particles with high density coating for inducing antibody expression 艾滋基金研究所 2024-03-22 CN disclosed
CN-117500931-A measles-HIV or measles-HTLV vaccine 维洛克塞斯 2024-02-02 CN disclosed
WO-2024015741-A1 HIV IMMUNOGENIC POLYPEPTIDES AND VACCINES AND USES THEREOF GILEAD SCIENCES, INC. (US) 2024-01-18 WO disclosed
CN-116171165-A HIV-1 antibodies 墨尔本大学 2023-05-26 CN disclosed
CN-115010805-A HIV-1 GP41 neutralizing antibodies and uses thereof 美国政府(由卫生和人类服务部的部长所代表) 2022-09-06 CN disclosed
CN-107375919-B Methods and compositions for antiviral immunization 台湾地区“中央研究院” 2022-07-29 CN disclosed
CN-108884149-B HIV-1 GP41 neutralizing antibodies and uses thereof 美国政府(由卫生和人类服务部的部长所代表) 2022-07-01 CN disclosed
CN-114478796-A Modified human immunodeficiency virus membrane protein and application thereof 厦门大学 2022-05-13 CN disclosed
CN-108137676-B gp120 neutralizing antibodies and uses thereof 美国政府(由卫生和人类服务部的部长所代表) 2022-03-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250177373-A1 COMPOSITIONS AND METHODS FOR TARGETING A VIRAL INFECTION HAVCR2, CD4, MAVS BACE1 653/4885VIPR2 2337/4885VIPR1 797/4885
US-12064425-B2 Compositions and methods for targeting a viral infection HAVCR2, CD4, MAVS BACE1 653/4885VIPR2 2337/4885VIPR1 797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.