Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | NNMT | P40261 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128526 | 1.00 | MEN1 (0.68) | MEN1KMT2ANNMTL3MBTL1NPSR1 | |
| SCHEMBL4120256 | 0.91 | MEN1 (0.58) | MEN1KMT2ANNMTL3MBTL1NPSR1 | |
| Trifluoroacetic Acid SCHEMBL29618259 | 0.88 | MEN1 (0.59) | MEN1KMT2ANNMTL3MBTL1NPSR1 | |
| Oxiniacic Acid SCHEMBL129209 | 0.81 | MEN1 (1.00) | MEN1KMT2AL3MBTL1CYP3A4TSHR | |
| Oxiniacic Acid SCHEMBL29766756 | 0.81 | MEN1 (1.00) | MEN1KMT2AL3MBTL1CYP3A4TSHR | |
| SCHEMBL2772084 | 0.79 | MEN1 (0.68) | MEN1KMT2ANNMTL3MBTL1CYP3A4 | |
| SCHEMBL9083270 | 0.79 | MEN1 (0.68) | MEN1KMT2ANNMTL3MBTL1CYP3A4 | |
| SCHEMBL5699279 | 0.79 | KMT2A (0.57) | MEN1KMT2ANNMTL3MBTL1RECQL | |
| SCHEMBL212234 | 0.79 | MEN1 (0.68) | MEN1KMT2ANNMTL3MBTL1MAPT | |
| SCHEMBL25846405 | 0.79 | MEN1 (0.57) | MEN1KMT2ANNMTL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144235-A1 | METHODS FOR MONITORING AND TREATING WARBURG EFFECT IN PATIENTS WITH PI3K-RELATED DISORDERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-08-03 | — | — | WO | claimed |
| EP-4472735-A2 | METHODS OF DETECTING AND TREATING CEREBRAL ANEURYSMS | University of Pittsburgh - of the Commonwealth System of Higher Education (US) | 2024-12-11 | — | — | EP | disclosed |
| EP-4243822-A1 | USE OF PHARMACEUTICAL DOSES OF NIACIN, OR AN ANALOG THEREOF, FOR THE REGRESSION OR REVERSAL OF FIBROSIS AND/OR LIVER CIRRHOSIS | The Regents of The University of California (US) | 2023-09-20 | — | — | EP | disclosed |
| WO-2023150294-A2 | METHODS OF DETECTING AND TREATING CEREBRAL ANEURYSMS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023144235-A1 | METHODS FOR MONITORING AND TREATING WARBURG EFFECT IN PATIENTS WITH PI3K-RELATED DISORDERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023044455-A2 | RNA STABILIZATION | TEAM MEDICAL LLC (US) | 2023-03-23 | — | — | WO | disclosed |
| CN-115724847-A | 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives | 拜耳知识产权有限责任公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-101631464-B | 2,3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives for the treatment of hyperproliferative diseases and angiogenesis-related diseases | 拜耳知识产权有限责任公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-108774232-B | 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives | 拜耳知识产权有限责任公司 | 2022-08-09 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |
| CN-105254634-B | 2, 3-dihydroimidazo [1,2-c ] quinazoline substituted derivatives useful in the treatment of hyperproliferative diseases and angiogenesis-related diseases | 拜耳知识产权有限责任公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2022104289-A1 | USE OF PHARMACEUTICAL DOSES OF NIACIN, OR AN ANALOG THEREOF, FOR THE REGRESSION OR REVERSAL OF FIBROSIS AND/OR LIVER CIRRHOSIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-19 | — | — | WO | disclosed |