SCHEMBL128526

SCHEMBL128526

NC(=O)c1ccc[n+]([O-])c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
NNMT P40261 1/20 0.60
L3MBTL1 Q9Y468 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MAPT P10636 2/20 0.48
CYP3A4 P08684 2/20 0.48
POLB P06746 1/20 0.48
PARP1 P09874 1/20 0.48
TSHR P16473 1/20 0.48
CYP2C19 P33261 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
GPR84 Q9NQS5 2/20 0.47
ABL1 P00519 1/20 0.44
RIN1 Q13671 1/20 0.44
HSP90AA1 P07900 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29618255 1.00 MEN1 (0.68) MEN1KMT2ANNMTL3MBTL1NPSR1
SCHEMBL4120256 0.91 MEN1 (0.58) MEN1KMT2ANNMTL3MBTL1NPSR1
Trifluoroacetic Acid SCHEMBL29618259 0.88 MEN1 (0.59) MEN1KMT2ANNMTL3MBTL1NPSR1
Oxiniacic Acid SCHEMBL129209 0.81 MEN1 (1.00) MEN1KMT2AL3MBTL1CYP3A4TSHR
Oxiniacic Acid SCHEMBL29766756 0.81 MEN1 (1.00) MEN1KMT2AL3MBTL1CYP3A4TSHR
SCHEMBL2772084 0.79 MEN1 (0.68) MEN1KMT2ANNMTL3MBTL1CYP3A4
SCHEMBL9083270 0.79 MEN1 (0.68) MEN1KMT2ANNMTL3MBTL1CYP3A4
SCHEMBL5699279 0.79 KMT2A (0.57) MEN1KMT2ANNMTL3MBTL1RECQL
SCHEMBL212234 0.79 MEN1 (0.68) MEN1KMT2ANNMTL3MBTL1MAPT
SCHEMBL25846405 0.79 MEN1 (0.57) MEN1KMT2ANNMTL3MBTL1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1647 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
US-20240290431-A1 BIOMARKER AND DIAGNOSIS SYSTEM FOR COLORECTAL CANCER DETECTION HANGZHOU CALIBRA DIAGNOSTICS CO LTD (CN) 2024-08-29 US claimed
WO-2023195790-A1 METHOD FOR MANUFACTURING BIOMATERIAL FOR TISSUE REPAIR WITH EXCELLENT SAFETY ㈜아크로스 2023-10-12 WO claimed
WO-2023156070-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2023-08-24 WO claimed
WO-2023156069-A1 COSMETIC COMPOSITION COMPRISING EXTRACT OF OPHIOPOGON JAPONICUS AND AT LEAST ONE CERAMIDE THE BOOTS COMPANY PLC (GB) 2023-08-24 WO claimed
WO-2023144235-A1 METHODS FOR MONITORING AND TREATING WARBURG EFFECT IN PATIENTS WITH PI3K-RELATED DISORDERS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-08-03 WO claimed
US-20230204604-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE SOCIETE DES PRODUITS NESTLE S.A. (CH) 2023-06-29 US claimed
US-20230157939-A1 PERSONAL CARE COMPOSITIONS WITH ENHANCED SOLUBILITY ACTIVES CONOPCO, INC., D/B/A UNILEVER (US) 2023-05-25 US claimed
US-20230101362-A1 RNA STABILIZATION TEAM MEDICAL LLC 2023-03-30 US claimed
EP-4142677-A1 PERSONAL CARE COMPOSITIONS WITH ENHANCED SOLUBILITY ACTIVES Unilever IP Holdings B.V. (NL) 2023-03-08 EP claimed
WO-1999006052-A1 METHODS OF PRETREATING HYPERLIPIDEMIC INDIVIDUALS WITH A FLUSH INHIBITING AGENT PRIOR TO THE START OF SINGLE DAILY DOSE NICOTINIC ACID THERAPY TO REDUCE FLUSHING PROVOKED BY NICOTINIC ACID KOS PHARMACEUTICALS, INC. (US) 1999-02-11 WO claimed
WO-1999006035-A2 COMBINATIONS OF HMG-CoA REDUCTASE INHIBITORS AND NICOTINIC ACID COMPOUNDS AND METHODS FOR TREATING HYPERLIPIDEMIA ONCE A DAY AT NIGHT KOS PHARMACEUTICALS, INC. (US) 1999-02-11 WO claimed
US-5512588-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-04-30 US claimed
US-5472687-A A water in oil or oil in water emulsion for treating hair loss ; free of hypotensive agent, side-effect reduction PROCTOR PETER H (US) 1995-12-05 US claimed
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP claimed
EP-0355612-B1 Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1994-07-27 EP claimed
US-5308857-A Antiulcer agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-05-03 US claimed
EP-0355612-A2 Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-02-28 EP claimed
US-4568628-A Water developable diazo printing plate composition with quaternary nitrogen stabilizer POLYCHROME CORPORATION (US) 1986-02-04 US claimed
US-4514408-A INHIBITORS OF GASTRIC SECRETION SANOFI (FR) 1985-04-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157939-A1 PERSONAL CARE COMPOSITIONS WITH ENHANCED SOLUBILITY ACTIVES CUTA, CBS, SLC7A11 MEN1 3851/4885KMT2A 2100/4885NNMT 124/4885
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 MEN1 3658/4885KMT2A 119/4885NNMT 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.