Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 3/20 | 0.42 |
| ▸ | CCR5 | P51681 | 3/20 | 0.42 |
| ▸ | CCR8 | P51685 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29618959 | 0.89 | AHR (0.45) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL574760 | 0.81 | GRM4 (0.61) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL29478404 | 0.81 | GRM4 (0.61) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL5779426 | 0.73 | AHR (0.47) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL21295711 | 0.73 | AHR (0.47) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL12278511 | 0.73 | AHR (0.53) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL12277930 | 0.73 | AHR (0.53) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL24776300 | 0.72 | KDM4E (0.54) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL12278333 | 0.72 | AHR (0.56) | AHRKDM4ETP53SMN1; SMN2HSD17B10 | |
| SCHEMBL12278688 | 0.71 | CYP1A2 (0.62) | AHRKDM4ETP53SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089377-A1 | COMBINATION OF A PD-1 OR PD-L1 ANTAGONIST AND A VEGFR INHIBITOR FOR TREATING CANCER | Taizhou Eoc Pharma Co., Ltd. (CN) | 2022-05-05 | — | — | WO | disclosed |