Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | NMT2 | O60551 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630341 | 0.99 | ERAP2 (0.47) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL29473878 | 0.96 | NMT2 (0.47) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL29462935 | 0.95 | ERAP2 (0.45) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL30478747 | 0.95 | NMT2 (0.49) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL29378561 | 0.95 | NMT2 (0.48) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL29592591 | 0.92 | NMT1 (0.52) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL31343172 | 0.92 | NPY4R (0.52) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL29714947 | 0.92 | ERAP2 (0.55) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL30785147 | 0.92 | ERAP2 (0.55) | ERAP2ERAP1LNPEPCPB2FOLH1 | |
| SCHEMBL29404079 | 0.92 | NPY4R (0.52) | ERAP2ERAP1LNPEPCPB2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237445-A2 | COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM | Research Institute at Nationwide Children's Hospital (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-116490778-A | Compositions and methods for preventing, inhibiting, disrupting or treating a multi-microbial biofilm | 国家儿童医院研究所 | 2023-07-25 | — | — | CN | disclosed |
| CN-116096239-A | Combination therapy for the treatment and prevention of biological membranes | 国家儿童医院研究所 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022094433-A2 | COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) | 2022-05-05 | — | — | WO | disclosed |