Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | STS | P08842 | 2/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461356 | 1.00 | KDM4E (0.39) | KDM4EJAK1JAK2CNR1TYK2 | |
| SCHEMBL30552427 | 0.83 | — | — | |
| SCHEMBL24461500 | 0.78 | JAK1 (0.43) | KDM4EJAK1JAK2CNR1TYK2 | |
| SCHEMBL29619438 | 0.78 | CNR1 (0.48) | KDM4EJAK1JAK2CNR1TYK2 | |
| SCHEMBL24461631 | 0.78 | CNR1 (0.48) | KDM4EJAK1JAK2CNR1TYK2 | |
| SCHEMBL24461328 | 0.77 | KDM4E (0.40) | KDM4EJAK1JAK2TYK2JAK3 | |
| SCHEMBL29619389 | 0.77 | KDM4E (0.40) | KDM4EJAK1JAK2TYK2JAK3 | |
| SCHEMBL24461562 | 0.74 | MAPT (0.47) | KDM4EJAK1JAK2CNR1TYK2 | |
| SCHEMBL30986433 | 0.73 | KDM4E (0.42) | KDM4EJAK1JAK2TYK2JAK3 | |
| SCHEMBL30658057 | 0.73 | KDM4E (0.40) | KDM4EJAK1JAK2CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109426-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |