Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461631 | 1.00 | CNR1 (0.48) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL24461562 | 0.85 | MAPT (0.47) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL24461526 | 0.82 | SMARCA2 (0.53) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL29619399 | 0.82 | SMARCA2 (0.53) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL29619377 | 0.78 | KDM4E (0.39) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL24461356 | 0.78 | KDM4E (0.39) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL26683361 | 0.77 | MAPT (0.44) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL30666276 | 0.77 | MAPT (0.44) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL31424848 | 0.75 | ESR2 (0.40) | CNR1MAPTKDM4ETHRBJAK2 | |
| SCHEMBL30658028 | 0.74 | MAPT (0.54) | CNR1MAPTKDM4ETHRBJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744929-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022109426-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |