Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 9/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 7/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 7/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 6/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461188 | 1.00 | JAK3 (0.41) | JAK3PBRM1SMARCA2SMARCA4GSTO1 | |
| SCHEMBL30552692 | 0.87 | PBRM1 (0.39) | PBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL24461456 | 0.86 | PBRM1 (0.46) | PBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL24461240 | 0.86 | PBRM1 (0.40) | PBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL31505643 | 0.86 | JAK3 (0.35) | JAK3PBRM1SMARCA2SMARCA4GSTO1 | |
| SCHEMBL31505601 | 0.86 | JAK3 (0.35) | JAK3PBRM1SMARCA2SMARCA4GSTO1 | |
| SCHEMBL31505688 | 0.85 | SMARCA2 (0.35) | JAK3PBRM1SMARCA2SMARCA4GSTO1 | |
| SCHEMBL31505636 | 0.84 | JAK3 (0.39) | JAK3PBRM1SMARCA2SMARCA4GSTO1 | |
| SCHEMBL31505567 | 0.84 | JAK3 (0.39) | JAK3PBRM1SMARCA2SMARCA4GSTO1 | |
| SCHEMBL31505711 | 0.84 | JAK3 (0.39) | JAK3PBRM1SMARCA2SMARCA4GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101944-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2025-05-15 | — | — | WO | claimed |
| WO-2025101944-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |
| CN-116744929-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022109426-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |