Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 4/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.35 |
| ▸ | BTK | Q06187 | 13/20 | 0.34 |
| ▸ | TXK | P42681 | 10/20 | 0.34 |
| ▸ | ITK | Q08881 | 10/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | TEC | P42680 | 6/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461188 | 0.85 | JAK3 (0.41) | SMARCA2SMARCA4PBRM1BTKJAK3 | |
| SCHEMBL29619408 | 0.85 | JAK3 (0.41) | SMARCA2SMARCA4PBRM1BTKJAK3 | |
| SCHEMBL31505680 | 0.82 | PBRM1 (0.34) | SMARCA2SMARCA4PBRM1BRD4 | |
| SCHEMBL31505636 | 0.80 | JAK3 (0.39) | SMARCA2SMARCA4PBRM1BTKJAK3 | |
| SCHEMBL31505711 | 0.80 | JAK3 (0.39) | SMARCA2SMARCA4PBRM1BTKJAK3 | |
| SCHEMBL31505567 | 0.80 | JAK3 (0.39) | SMARCA2SMARCA4PBRM1BTKJAK3 | |
| SCHEMBL27052462 | 0.77 | PBRM1 (0.41) | SMARCA2SMARCA4PBRM1BRD4 | |
| SCHEMBL24461456 | 0.76 | PBRM1 (0.46) | SMARCA2SMARCA4PBRM1BRD4 | |
| SCHEMBL31505643 | 0.76 | JAK3 (0.35) | SMARCA2SMARCA4PBRM1BTKJAK3 | |
| SCHEMBL31505601 | 0.76 | JAK3 (0.35) | SMARCA2SMARCA4PBRM1BTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101944-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |