SCHEMBL29619624

SCHEMBL29619624

N#Cc1cc(Oc2ccc(N)cc2)cc(Oc2ccc(N)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
TDP1 Q9NUW8 2/20 0.58
CYP3A4 P08684 1/20 0.58
TSHR P16473 1/20 0.58
MAPT P10636 5/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
MITF O75030 1/20 0.57
GAA P10253 1/20 0.57
GFER P55789 1/20 0.57
NLRP1 Q9C000 1/20 0.57
NOD2 Q9HC29 1/20 0.57
RAB9A P51151 3/20 0.55
NPC1 O15118 2/20 0.55
NLRP3 Q96P20 1/20 0.55
MAOA P21397 2/20 0.50
TEAD4 Q15561 1/20 0.48
MAOB P27338 1/20 0.48
POLB P06746 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11428077 0.87 ALDH1A1 (0.69) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL5464974 0.87 ALDH1A1 (0.64) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL852039 0.86 MEN1 (0.53) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL13192848 0.85 ALDH1A1 (0.66) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL30063 0.84 ALDH1A1 (0.82) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL29582194 0.82 PARP15 (0.57) ALDH1A1TSHRMAPTSMN1; SMN2MEN1
SCHEMBL7074955 0.81 MAOB (0.58) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL7073983 0.80 CYP19A1 (0.54) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL12583968 0.80 ALDH1A1 (0.54) ALDH1A1TDP1CYP3A4TSHRMAPT
SCHEMBL23759 0.80 MEN1 (0.79) ALDH1A1TDP1CYP3A4TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114644829-B Polyaramide/polyetherimide high-temperature energy storage blend film dielectric material and preparation method and application thereof 吉林大学 2023-03-24 CN disclosed
CN-114644829-A Polyaramide/polyetherimide high-temperature energy storage blend film dielectric material and preparation method and application thereof 吉林大学 2022-06-21 CN disclosed