Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25368595 | 1.00 | ATM (0.37) | ATMAGTR2MMP2ANPEPRAB9A | |
| SCHEMBL1251163 | 0.84 | ATM (0.42) | ATMAGTR2MMP2ANPEP | |
| SCHEMBL21682443 | 0.84 | ATM (0.42) | ATMAGTR2MMP2ANPEP | |
| SCHEMBL1251161 | 0.84 | ATM (0.42) | ATMAGTR2MMP2ANPEP | |
| SCHEMBL1251167 | 0.84 | ATM (0.42) | ATMAGTR2MMP2ANPEP | |
| SCHEMBL6917231 | 0.84 | ATM (0.42) | ATMAGTR2MMP2ANPEP | |
| SCHEMBL20566560 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL20570544 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL16717011 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL16717012 | 0.83 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054591-A1 | COMBINATION THERAPY FOR TREATING CANCER | Astrazeneca AB (SE) | 2022-09-14 | — | — | EP | disclosed |
| CN-114599372-A | Combination therapy for the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2022-06-07 | — | — | CN | disclosed |