Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.44 |
| ▸ | GABRP | O00591 | 6/20 | 0.44 |
| ▸ | GABRD | O14764 | 6/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.44 |
| ▸ | GABRE | P78334 | 6/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574789 | 1.00 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30968739 | 0.92 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5846548 | 0.92 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28574787 | 0.89 | KDM4E (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28983540 | 0.88 | CYP2C9 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30924884 | 0.88 | CYP2C9 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8758676 | 0.87 | KDM5A (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29619773 | 0.87 | KDM5A (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2338977 | 0.85 | KDM5A (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL23501076 | 0.84 | CYP4F2 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114644565-A | Synthesis method of key intermediate of imidazolone compound | 江苏中旗科技股份有限公司 | 2022-06-21 | — | — | CN | disclosed |