Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360009 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMMP13MMP2 | |
| SCHEMBL27637998 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMMP13MMP2 | |
| SCHEMBL4816985 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMMP13MMP2 | |
| SCHEMBL2810966 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL4866756 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMMP13MMP2 | |
| SCHEMBL28110970 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL30129995 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL28110425 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL2230388 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL29642602 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240741-A1 | IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND THEIR USE AS ATM KINASE INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022096361-A1 | IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND THEIR USE AS ATM KINASE INHIBITORS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2022-05-12 | — | — | WO | disclosed |