Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28880275 | 0.89 | — | — | |
| Formaldehyde SCHEMBL248046 | 0.89 | — | — | |
| Formaldehyde SCHEMBL27471860 | 0.89 | — | — | |
| Formaldehyde SCHEMBL9311319 | 0.89 | — | — | |
| Formaldehyde SCHEMBL179837 | 0.89 | — | — | |
| Formaldehyde SCHEMBL23581487 | 0.89 | — | — | |
| Formaldehyde SCHEMBL28170357 | 0.89 | — | — | |
| Formaldehyde SCHEMBL21569406 | 0.80 | — | — | |
| Formaldehyde SCHEMBL8203913 | 0.80 | — | — | |
| Formaldehyde SCHEMBL21569388 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115154470-B | Methods of treating depression using orexin-2 receptor antagonists | 詹森药业有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115154470-A | Methods of treating depression using orexin-2 receptor antagonists | 詹森药业有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-108883110-B | Methods of treating depression using orexin-2 receptor antagonists | 詹森药业有限公司 | 2022-05-27 | — | — | CN | disclosed |