Formaldehyde

Formaldehyde

SCHEMBL179837

C=O.O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL248046 1.00
Formaldehyde SCHEMBL23581487 1.00
Formaldehyde SCHEMBL28880275 1.00
Formaldehyde SCHEMBL27471860 1.00
Formaldehyde SCHEMBL8203913 0.89
Formaldehyde SCHEMBL21569406 0.89
Formaldehyde SCHEMBL21569408 0.89
Formaldehyde SCHEMBL21569388 0.89
Formaldehyde SCHEMBL25244636 0.89
Formaldehyde SCHEMBL3689972 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5122 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120646849-B Preparation method and application of lithium battery negative electrode material and lithium ion battery HUBEI UNIVERSITY (CN) 2026-05-26 CN claimed
US-20250229228-A1 ELECTROCHEMICAL DIRECT AIR CAPTURE OF CO2 USING REDOX-ACTIVE TEXTILES UNIVERSITY OF MASSACHUSETTS 2025-07-17 US claimed
CN-120154014-A Bactericide for circulating water and preparation method thereof 珠海津环环保工程有限公司 2025-06-17 CN claimed
CN-120005234-A Microcapsule with alkaline environment and mechanical dual response, and preparation method and application thereof 北京工业大学 2025-05-16 CN claimed
CN-119977771-A Multivariable predictive control formaldehyde aqueous solution optimization control method 晋能控股装备制造集团天源山西化工有限公司 2025-05-13 CN claimed
CN-118515830-B Preparation method of heteroatom doped phenolic resin nano adsorbent and application of heteroatom doped phenolic resin nano adsorbent in selective separation of palladium 濮阳天河化工总厂 2025-04-25 CN claimed
CN-119793416-A Rubidium cesium ion adsorption material and preparation method and application thereof 中国石油化工股份有限公司 2025-04-11 CN claimed
CN-119798761-A Preparation method of sound-insulating noise-reducing sponge and application of sound-insulating noise-reducing sponge in air conditioner 珠海中亚空调配件有限公司 2025-04-11 CN claimed
CN-119797811-A Water reducer composition and preparation method and application thereof 浙江广天构件集团股份有限公司 2025-04-11 CN claimed
CN-119797850-A MICP-fiber synergistic curing mortar and production process thereof 广州大学 2025-04-11 CN claimed
EP-0004543-B1 PROCESS FOR THE PREPARATION OF LOW-MOLECULAR POLYHYDROXY COMPOUNDS AND THEIR USE FOR THE PREPARATION OF POLYURETHANE RESINS BAYER AG (DE) 1981-06-10 EP claimed
EP-0001210-B1 MIXTURES CAPABLE OF REACTING WITH ISOCYANATES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN A PROCESS FOR THE PRODUCTION OF POLYURETHANE-PLASTICS BAYER AG (DE) 1981-04-01 EP claimed
US-4255529-A Process for the preparation of cellular or non-cellular polyurethane resins BAYER AKTIENGESELLSCHAFT (DE) 1981-03-10 US claimed
US-4247653-A CONDENSATION OF FORMALDEHYDE BAYER AKTIENGESELLSCHAFT (DE) 1981-01-27 US claimed
US-4247654-A Alkoxylated formose polyols and their use in polyurethane plastics BAYER AKTIENGESELLSCHAFT (DE) 1981-01-27 US claimed
EP-0000912-B1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR POLYHYDROXY COMPOUNDS BAYER AG (DE) 1980-10-01 EP claimed
US-4221876-A HYDROXYMETHYLATION OF ALDEHYDES AND KETONES BAYER AKTIENGESELLSCHAFT (DE) 1980-09-09 US claimed
US-4205138-A PREPARED BY CONDENSATION OF FORMALDEHYDE HYDRATE BAYER AKTIENGESELLSCHAFT (DE) 1980-05-27 US claimed
US-4187356-A Condensation of formaldehyde hydrate to form mixtures which, together with monomers capable of aminoplast formation are useful in the preparation of polyurethane foams BAYER AKTIENGESELLSCHAFT (DE) 1980-02-05 US claimed
US-4156636-A CONDENSATION OF FORMALDEHYDE HYDRATE, BASEFICIATION WITH CALCIUM HYDROXIDE BAYER AKTIENGESELLSCHAFT (DE) 1979-05-29 US claimed