Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24333485 | 1.00 | LPL (0.46) | LPLLIPGFFAR1HIF1ANR1I2 | |
| SCHEMBL5781912 | 0.88 | LPL (0.45) | LPLLIPGFFAR1F2F11 | |
| SCHEMBL12205425 | 0.87 | LPL (0.41) | LPLLIPGFFAR1HIF1ANR1I2 | |
| SCHEMBL17350120 | 0.87 | LPL (0.41) | LPLLIPGFFAR1HIF1ANR1I2 | |
| SCHEMBL15392902 | 0.87 | LPL (0.44) | LPLLIPGFFAR1HIF1AF2 | |
| SCHEMBL4430468 | 0.86 | LPL (0.46) | LPLLIPGFFAR1F2F11 | |
| SCHEMBL9948194 | 0.83 | LPL (0.57) | LPLLIPGFFAR1P2RX7F2 | |
| SCHEMBL13468810 | 0.83 | LPL (0.39) | LPLLIPGFFAR1HIF1ANR1I2 | |
| SCHEMBL20357964 | 0.81 | LPL (0.37) | LPLLIPGFFAR1HIF1ANR1I2 | |
| SCHEMBL23909384 | 0.81 | LPL (0.41) | LPLLIPGFFAR1HIF1ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082174-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO OPERATING COMPANY INC. (US) | 2022-04-21 | — | — | WO | disclosed |