SCHEMBL29620186

SCHEMBL29620186

COc1ccc2ccccc2c1CO

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.58
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
POLB P06746 1/20 0.52
CETP P11597 1/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702988 1.00 MAPT (0.58) MAPTKMT2AMEN1POLBCETP
SCHEMBL7196887 0.86 MAPT (0.55) MAPTKMT2AMEN1POLBCETP
SCHEMBL23515212 0.85 CETP (0.52) MAPTKMT2AMEN1POLBCETP
SCHEMBL19766698 0.85 MAPT (0.62) MAPTKMT2AMEN1POLBCETP
SCHEMBL11893003 0.83 KMT2A (0.60) MAPTKMT2AMEN1POLBSMN1; SMN2
SCHEMBL15414250 0.82 ALOX5 (0.51) KMT2AKDM4E
SCHEMBL19610235 0.81 MAPT (0.58) MAPTKMT2AMEN1POLBCETP
SCHEMBL5236602 0.81 MAPT (0.58) MAPTKMT2AMEN1POLBSMN1; SMN2
SCHEMBL4698919 0.81 MAPT (0.58) MAPTKMT2AMEN1POLBCETP
SCHEMBL15798428 0.81 MAPT (0.58) MAPTKMT2AMEN1POLBCETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022081133-A1 MODIFIED POROUS WICKING MEMBRANES HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-04-21 WO disclosed