Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14441424 | 0.94 | ALDH1A1 (0.53) | MAPTPOLBLMNANPSR1KDM4E | |
| SCHEMBL16348229 | 0.92 | TSHR (0.62) | MAPTPOLBLMNANPSR1KDM4E | |
| SCHEMBL10700083 | 0.92 | TSHR (0.55) | MAPTPOLBLMNANPSR1SMN1; SMN2 | |
| SCHEMBL1496548 | 0.92 | TSHR (0.62) | MAPTPOLBLMNANPSR1KDM4E | |
| SCHEMBL1496665 | 0.92 | POLB (0.57) | MAPTPOLBLMNANPSR1KDM4E | |
| SCHEMBL11700114 | 0.90 | ALDH1A1 (0.52) | MAPTPOLBLMNANPSR1ALDH1A1 | |
| SCHEMBL6049252 | 0.90 | TDP1 (0.55) | MAPTPOLBLMNANPSR1KDM4E | |
| SCHEMBL12663754 | 0.90 | MAPK1 (0.62) | MAPTPOLBLMNANPSR1KDM4E | |
| SCHEMBL1496758 | 0.90 | MAPK1 (0.62) | MAPTPOLBLMNANPSR1KDM4E | |
| SCHEMBL12305419 | 0.90 | BACE1 (0.49) | MAPTPOLBLMNANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539318-B | Ring-opened cucurbituril phosphate compound, preparation thereof and application thereof in medicine solubilization | 武汉工程大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-114539318-A | Ring-opened cucurbituril phosphate compound, preparation thereof and application thereof in drug solubilization | 武汉工程大学 | 2022-05-27 | — | — | CN | disclosed |