Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 3/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24345288 | 1.00 | POLB (0.35) | POLBTMEM97SIGMAR1DYRK1ACFTR | |
| SCHEMBL24345698 | 1.00 | POLB (0.35) | POLBTMEM97SIGMAR1DYRK1ACFTR | |
| SCHEMBL24345316 | 0.92 | POLB (0.35) | POLBTMEM97SIGMAR1DYRK1ACFTR | |
| SCHEMBL29620716 | 0.92 | POLB (0.35) | POLBTMEM97SIGMAR1DYRK1ACFTR | |
| SCHEMBL24345858 | 0.92 | POLB (0.35) | POLBTMEM97SIGMAR1DYRK1ACFTR | |
| SCHEMBL24345870 | 0.91 | POLB (0.36) | POLBDYRK1ACFTRGABRA5MEN1 | |
| SCHEMBL24345459 | 0.90 | POLB (0.39) | POLBDYRK1ACFTRGABRA5MEN1 | |
| SCHEMBL24345472 | 0.89 | POLB (0.35) | POLBDYRK1AMEN1HPGDKMT2A | |
| SCHEMBL24346314 | 0.89 | POLB (0.35) | POLBDYRK1AMEN1HPGDKMT2A | |
| SCHEMBL29620707 | 0.89 | POLB (0.35) | POLBDYRK1AMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086840-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |