Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 9/20 | 0.40 |
| ▸ | VCP | P55072 | 4/20 | 0.38 |
| ▸ | FLT1 | P17948 | 7/20 | 0.37 |
| ▸ | FLT4 | P35916 | 7/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925709 | 1.00 | ALOX5 (0.47) | ALOX5KDRVCPFLT1FLT4 | |
| SCHEMBL24637017 | 0.88 | TRPV1 (0.48) | ALOX5KDRVCPFLT1FLT4 | |
| SCHEMBL29620978 | 0.88 | ALOX5 (0.38) | ALOX5KDRVCPFLT1FLT4 | |
| SCHEMBL22925612 | 0.88 | ALOX5 (0.38) | ALOX5KDRVCPFLT1FLT4 | |
| SCHEMBL22925599 | 0.86 | ALOX5 (0.34) | ALOX5KDRNPC1RAB9AMEN1 | |
| SCHEMBL22925708 | 0.81 | ALOX5 (0.46) | ALOX5KDRVCPFLT1FLT4 | |
| SCHEMBL28733644 | 0.81 | ALOX5 (0.46) | ALOX5KDRVCPFLT1FLT4 | |
| SCHEMBL22925712 | 0.75 | ALOX5 (0.47) | ALOX5KDRVCPFLT1FLT4 | |
| SCHEMBL22925659 | 0.74 | TRPV1 (0.45) | KDRHDAC1HDAC6TRPV1 | |
| SCHEMBL29696299 | 0.74 | TRPV1 (0.45) | KDRHDAC1HDAC6TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |