Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | FLT4 | P35916 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24636937 | 1.00 | NPSR1 (0.39) | NPSR1KDM4ETRPV1CCR6KDR | |
| SCHEMBL22926082 | 0.86 | TRPV1 (0.47) | TRPV1CCR6KDRFLT1FLT4 | |
| SCHEMBL22925935 | 0.85 | CHEK1 (0.38) | NPSR1KDM4ETRPV1CCR6KDR | |
| SCHEMBL22925604 | 0.85 | KDR (0.35) | KDRFLT1FLT4NPC1RAB9A | |
| SCHEMBL22925932 | 0.83 | CHEK1 (0.39) | NPSR1KDM4EKDRFLT1FLT4 | |
| SCHEMBL22925792 | 0.83 | KDR (0.35) | KDM4EKDRFLT1FLT4NPC1 | |
| SCHEMBL24637089 | 0.78 | NPSR1 (0.38) | NPSR1KDM4ETRPV1KDRFLT1 | |
| SCHEMBL22925781 | 0.77 | KMT2A (0.36) | NPSR1KDM4ETRPV1PTGS1NPC1 | |
| SCHEMBL22925941 | 0.77 | KMT2A (0.36) | NPSR1KDM4ETRPV1PTGS1NPC1 | |
| SCHEMBL29696311 | 0.77 | KMT2A (0.36) | NPSR1KDM4ETRPV1PTGS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |