Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925738 | 1.00 | HDAC4 (0.40) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL28733649 | 0.79 | NOTUM (0.46) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL29621141 | 0.79 | NOTUM (0.46) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL22925925 | 0.76 | MAPT (0.40) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL29559433 | 0.76 | MAPT (0.40) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL22925831 | 0.76 | HDAC4 (0.49) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL29620876 | 0.76 | HDAC4 (0.49) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL12805020 | 0.73 | KDM4E (0.40) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL29559680 | 0.73 | KDM4E (0.40) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL22897587 | 0.73 | MAPT (0.40) | HDAC4SMN1; SMN2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |