Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 5/20 | 0.62 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 6/20 | 0.47 |
| ▸ | FLT1 | P17948 | 5/20 | 0.47 |
| ▸ | FLT4 | P35916 | 5/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925926 | 1.00 | VCP (0.62) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL22925918 | 0.85 | VCP (0.44) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL22925496 | 0.84 | TRPV1 (0.47) | VCPKDRFLT1FLT4IMPDH2 | |
| SCHEMBL29620900 | 0.84 | KDR (0.45) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL28733673 | 0.84 | KDR (0.45) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL29620967 | 0.84 | TRPV1 (0.47) | VCPKDRFLT1FLT4IMPDH2 | |
| SCHEMBL24636886 | 0.83 | VCP (0.53) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL29621095 | 0.83 | VCP (0.53) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL22925978 | 0.83 | FLT1 (0.44) | VCPSIRT7KDRFLT1FLT4 | |
| SCHEMBL29620981 | 0.83 | FLT1 (0.44) | VCPSIRT7KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |