Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPRR | Q15256 | 1/20 | 0.43 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925908 | 1.00 | GSK3B (0.55) | GSK3BACHEHDAC1FPR2PDCD1 | |
| SCHEMBL29696325 | 0.86 | ACHE (0.47) | GSK3BACHEHDAC1NPSR1BCHE | |
| SCHEMBL22925909 | 0.86 | ACHE (0.47) | GSK3BACHEHDAC1NPSR1BCHE | |
| SCHEMBL22925920 | 0.82 | KDR (0.47) | ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL29620883 | 0.82 | KDR (0.47) | ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL22583494 | 0.72 | GSK3B (0.42) | GSK3BACHEHDAC1PDCD1CD274 | |
| SCHEMBL29999758 | 0.72 | GSK3B (0.42) | GSK3BACHEHDAC1PDCD1CD274 | |
| SCHEMBL29621004 | 0.71 | ACHE (0.49) | GSK3BACHENPSR1BCHEBACE1 | |
| SCHEMBL24653364 | 0.71 | GSK3B (0.46) | GSK3BACHEHDAC1FPR2NPSR1 | |
| SCHEMBL17377353 | 0.71 | GSK3B (1.00) | GSK3BACHEPDCD1CD274NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |