Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28733789 | 0.88 | KDR (0.36) | KDRTRPV1CYP1A2VCPALOX5 | |
| SCHEMBL28733793 | 0.88 | KDR (0.36) | KDRTRPV1CYP1A2ABL1BCR | |
| SCHEMBL22925922 | 0.88 | KDR (0.36) | KDRTRPV1CYP1A2ABL1BCR | |
| SCHEMBL28939252 | 0.80 | KDR (0.42) | KDRTRPV1CYP1A2FLT1FLT4 | |
| SCHEMBL29620883 | 0.79 | KDR (0.47) | KDRTRPV1VCPALOX5FLT1 | |
| SCHEMBL22925921 | 0.79 | VCP (0.46) | KDRTRPV1CYP1A2VCPALOX5 | |
| SCHEMBL22925920 | 0.79 | KDR (0.47) | KDRTRPV1VCPALOX5FLT1 | |
| SCHEMBL29620940 | 0.79 | VCP (0.46) | KDRTRPV1CYP1A2VCPALOX5 | |
| SCHEMBL24636896 | 0.75 | VCP (0.41) | KDRABL1BCRVCPALOX5 | |
| SCHEMBL29696270 | 0.75 | VCP (0.41) | KDRABL1BCRVCPALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |