Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 12/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29076828 | 0.98 | PGR (0.43) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL29621962 | 0.98 | PGR (0.43) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL29621937 | 0.95 | PGR (0.40) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL29621927 | 0.95 | PGR (0.40) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL29621911 | 0.84 | PGR (0.55) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL29622023 | 0.83 | PGR (0.48) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29621965 | 0.81 | PGR (0.52) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL29076750 | 0.81 | PGR (0.52) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL28530057 | 0.80 | PGR (0.46) | PGR | |
| SCHEMBL29622021 | 0.80 | PGR (0.46) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240722-A1 | OXINDOLES AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099066-A1 | OXINDOLES AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |