Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 7/20 | 0.50 |
| ▸ | MET | P08581 | 4/20 | 0.50 |
| ▸ | AURKA | O14965 | 3/20 | 0.50 |
| ▸ | TEK | Q02763 | 3/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24724243 | 1.00 | TNKS (0.51) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL29622884 | 1.00 | TNKS (0.51) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL22972144 | 0.88 | AKR1C3 (0.56) | KDRBRAFMAPK14TNNI3KF10 | |
| SCHEMBL29622993 | 0.88 | AKR1C3 (0.56) | KDRBRAFMAPK14TNNI3KF10 | |
| SCHEMBL24724269 | 0.87 | MEN1 (0.58) | KDRMETAURKATEKAURKB | |
| SCHEMBL24724268 | 0.85 | KDR (0.54) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL24724242 | 0.84 | KDR (0.50) | KDRMETAURKATEKAURKB | |
| SCHEMBL22972010 | 0.82 | MAPT (0.52) | KDRBRAFMAPK14TNNI3KF10 | |
| SCHEMBL22972360 | 0.80 | LOX (0.62) | MET | |
| SCHEMBL22972221 | 0.80 | LOX (0.52) | KDRBRAFMAPK14TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114391009-A | Quinoline derivatives as protein kinase inhibitors | BCI制药公司 | 2022-04-22 | — | — | CN | disclosed |