SCHEMBL29622955

SCHEMBL29622955

O=C(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
PKM P14618 1/20 0.56
HTT P42858 2/20 0.48
MAPT P10636 2/20 0.48
POLB P06746 1/20 0.45
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PDE4D Q08499 1/20 0.41
CYP19A1 P11511 2/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9518702 1.00 LMNA (0.56) LMNAPKMHTTMAPTPOLB
SCHEMBL9785194 0.91 LMNA (0.48) LMNAPKMHTTMAPTPOLB
SCHEMBL15756547 0.88 PDE4D (0.49) LMNAPKMHTTMAPTPOLB
SCHEMBL29110121 0.87 LMNA (0.55) LMNAPKMHTTMAPTPOLB
SCHEMBL14645540 0.87 LMNA (0.47) LMNAPKMHTTMAPTPOLB
SCHEMBL30172138 0.87 LMNA (0.47) LMNAPKMHTTMAPTPOLB
SCHEMBL2550587 0.86 LMNA (0.67) LMNAPKMHTTMAPTPOLB
SCHEMBL19994248 0.83 LMNA (0.48) LMNAPKMHTTMAPTPOLB
SCHEMBL15723513 0.83 LMNA (0.46) LMNAPKMHTTMAPTPOLB
SCHEMBL15732303 0.80 MAPT (0.51) LMNAPKMHTTMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143764-A Preparation method for synthesizing difenoconazole by four-step method 江西农业大学 2023-05-23 CN claimed
CN-114437049-A Preparation method for synthesizing difenoconazole by three-step method 江西农业大学 2022-05-06 CN claimed
CN-119350302-A Difenoxydim-p ring Synthesis method of azole 扬州大学 2025-01-24 CN disclosed
CN-116143764-A Preparation method for synthesizing difenoconazole by four-step method 江西农业大学 2023-05-23 CN disclosed
CN-114437049-A Preparation method for synthesizing difenoconazole by three-step method 江西农业大学 2022-05-06 CN disclosed