Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23162643 | 1.00 | LARS1 (0.38) | LARS1TUBB1AOC3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL29623275 | 0.98 | LARS1 (0.39) | LARS1TUBB1AOC3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL23162860 | 0.98 | LARS1 (0.39) | LARS1TUBB1AOC3HTR2AHTR2C | |
| SCHEMBL27819924 | 0.82 | TUBB1 (0.39) | TUBB1CA2CA4LMNAMAPT | |
| SCHEMBL22953956 | 0.81 | CA2 (0.52) | TUBB1CA2CA4LMNAMAPT | |
| SCHEMBL17221447 | 0.81 | CD274 (0.38) | LARS1HTR2AHTR2CTAAR1MAPT | |
| SCHEMBL7181230 | 0.79 | SLC2A1 (0.39) | TUBB1AOC3HTR2ACA2CA4 | |
| SCHEMBL17785347 | 0.79 | CD274 (0.40) | LARS1HTR2AHTR2CTAAR1L3MBTL1 | |
| SCHEMBL5304577 | 0.79 | HTR2A (0.49) | HTR2ATAAR1 | |
| SCHEMBL5304582 | 0.79 | HTR2A (0.49) | HTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450277-A | Substituted pyrimidines for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2022-05-06 | — | — | CN | disclosed |