Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 12/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15788155 | 1.00 | CSF1R (0.43) | CSF1RALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL130370 | 0.94 | CSF1R (0.43) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL25203373 | 0.87 | CSF1R (0.48) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL1877988 | 0.87 | CSF1R (0.48) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL2408634 | 0.87 | CSF1R (0.42) | CSF1RSMN1; SMN2GAAHPGDLPL | |
| SCHEMBL130052 | 0.85 | LPL (0.40) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL14552656 | 0.83 | LPL (0.40) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL26140779 | 0.82 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL1328329 | 0.82 | LPL (0.45) | CSF1RLPLLIPGCA1CA2 | |
| SCHEMBL8515009 | 0.82 | LPL (0.40) | CSF1RLPLLIPGCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713489-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110183440-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-04-22 | — | — | CN | disclosed |