Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865698 | 0.88 | HSD11B1 (0.49) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL19741714 | 0.88 | HSD11B1 (0.46) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL19741750 | 0.88 | HSD11B1 (0.46) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL19741749 | 0.88 | HSD11B1 (0.46) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL19741713 | 0.88 | HSD11B1 (0.46) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL29963502 | 0.88 | HSD11B1 (0.46) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL29963699 | 0.83 | HSD11B1 (0.43) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL29865914 | 0.83 | HSD11B1 (0.43) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL29866110 | 0.83 | HSD11B1 (0.43) | HSD11B1CHRM2POLBCHRM1CHRM4 | |
| SCHEMBL14177590 | 0.81 | MEN1 (0.48) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713489-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110183440-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-04-22 | — | — | CN | disclosed |