Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350890 | 1.00 | FGFR1 (0.57) | FGFR1MAPTALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL14748166 | 0.90 | FGFR1 (0.61) | FGFR1MAPTALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL19350770 | 0.87 | FGFR1 (0.71) | FGFR1MAPTALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL20627632 | 0.86 | FGFR1 (0.60) | FGFR1MAPTALDH1A1SMN1; SMN2SRC | |
| SCHEMBL12730486 | 0.83 | FGFR1 (0.76) | FGFR1ALDH1A1SRC | |
| Hydrochloric Acid SCHEMBL7990178 | 0.82 | FGFR1 (0.73) | FGFR1ALDH1A1SRC | |
| SCHEMBL31144722 | 0.81 | FGFR1 (0.51) | FGFR1MAPTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL3852532 | 0.77 | FGFR1 (0.54) | FGFR1MAPTALDH1A1SMN1; SMN2ATM | |
| SCHEMBL28336824 | 0.77 | FGFR1 (0.61) | FGFR1ALDH1A1ESR1ESR2SRC | |
| SCHEMBL19350738 | 0.77 | FGFR1 (0.79) | FGFR1MAPTALDH1A1SMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071523-B | Urea compound, preparation method and medical application thereof | 恩瑞生物医药科技（上海）有限公司 | 2022-05-31 | — | — | CN | disclosed |