Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18838111 | 1.00 | APP (0.45) | APPEGFRKDM4EKLK7KLK14 | |
| SCHEMBL21860493 | 1.00 | APP (0.45) | APPEGFRKDM4EKLK7KLK14 | |
| SCHEMBL18838109 | 1.00 | APP (0.45) | APPEGFRKDM4EKLK7KLK14 | |
| SCHEMBL18838100 | 0.94 | SLC16A3 (0.48) | APPEGFRALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL29623795 | 0.94 | SLC16A3 (0.48) | APPEGFRALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL18838101 | 0.94 | SLC16A3 (0.48) | APPEGFRALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL28726867 | 0.88 | PTPN1 (0.47) | APPEGFRKDM4EKLK7KLK14 | |
| SCHEMBL18867268 | 0.88 | ATM (0.46) | EGFRKDM4EALDH1A1S100A4SLC16A3 | |
| SCHEMBL18838150 | 0.88 | ATM (0.46) | EGFRKDM4EALDH1A1S100A4SLC16A3 | |
| SCHEMBL18838151 | 0.88 | ATM (0.46) | EGFRKDM4EALDH1A1S100A4SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699019-B | Benzofuran derivatives useful in the treatment of central nervous system and other diseases | 华纳巴布科克绿色化学学院有限公司 | 2022-05-10 | — | — | CN | disclosed |