SCHEMBL18838151

SCHEMBL18838151

N#CC(=Cc1ccc2cc(-c3ccc(Oc4ccccc4)cc3)oc2c1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
KDM4E B2RXH2 2/20 0.45
S100A4 P26447 1/20 0.44
MEN1 O00255 1/20 0.44
HSP90AA1 P07900 1/20 0.44
KMT2A Q03164 1/20 0.44
EGFR P00533 2/20 0.43
S1PR1 P21453 1/20 0.41
CISD1 Q9NZ45 1/20 0.40
SLC16A3 O15427 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
SLC16A1 P53985 1/20 0.40
GPR35 Q9HC97 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18838150 1.00 ATM (0.46) ATMKDM4ES100A4MEN1HSP90AA1
SCHEMBL18867268 1.00 ATM (0.46) ATMKDM4ES100A4MEN1HSP90AA1
SCHEMBL29623748 1.00 ATM (0.46) ATMKDM4ES100A4MEN1HSP90AA1
SCHEMBL21860493 0.88 APP (0.45) KDM4ES100A4MEN1KMT2AEGFR
SCHEMBL18838111 0.88 APP (0.45) KDM4ES100A4MEN1KMT2AEGFR
SCHEMBL18838109 0.88 APP (0.45) KDM4ES100A4MEN1KMT2AEGFR
SCHEMBL29623739 0.88 APP (0.45) KDM4ES100A4MEN1KMT2AEGFR
SCHEMBL18838138 0.85 MAPT (0.48) KDM4ES100A4EGFRCISD1SLC16A3
SCHEMBL18867245 0.85 MAPT (0.48) KDM4ES100A4EGFRCISD1SLC16A3
SCHEMBL18838135 0.85 MAPT (0.48) KDM4ES100A4EGFRCISD1SLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2024-06-25 US disclosed
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 US disclosed
EP-3374354-B1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS AMBIENT PHOTONICS INC (US) 2022-09-28 EP disclosed
CN-108699019-B Benzofuran derivatives useful in the treatment of central nervous system and other diseases 华纳巴布科克绿色化学学院有限公司 2022-05-10 CN disclosed
US-20210082632-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2021-03-18 US disclosed
EP-3621957-A1 STILBENE AND FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES Ambient Photonics, Inc. (US) 2020-03-18 EP disclosed
US-10590100-B2 Benzofuran derivatives for the treatment of CNS and other disorders Ambient Photonics, Inc. (US) 2020-03-17 US disclosed
US-20180346433-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2018-12-06 US disclosed
WO-2018208712-A1 STILBENE AND FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES WARNER BABCOCK INSITUTE FOR GREEN CHEMISTRY, LLC (US) 2018-11-15 WO disclosed
EP-3374354-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS The Warner-Babcock Institute For Green Chemistry LLC (US) 2018-09-19 EP disclosed
WO-2017083488-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS Warner Babcock Institute for Green Chemistry (US) 2017-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10590100-B2 Benzofuran derivatives for the treatment of CNS and other disorders PMP22, CDR2, CLN6 ATM 1372/4885KDM4E 3612/4885S100A4 2021/4885
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes FDFT1, SUN2, CDC73 ATM 375/4885KDM4E 2392/4885S100A4 2360/4885
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes FDFT1, SUN2, CDC73 ATM 375/4885KDM4E 2392/4885S100A4 2360/4885
US-20180346433-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS PMP22, CDR2, CLN6 ATM 1372/4885KDM4E 3612/4885S100A4 2021/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 ATM 419/4885KDM4E 1702/4885S100A4 2200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.