Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GABRP | O00591 | 1/20 | 0.57 |
| ▸ | GABRD | O14764 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.57 |
| ▸ | GABRE | P78334 | 1/20 | 0.57 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.57 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.57 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.57 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350708 | 1.00 | FGFR1 (0.71) | FGFR1MAPTSMN1; SMN2ALDH1A1GABRP | |
| SCHEMBL13836852 | 0.86 | FGFR1 (0.81) | FGFR1MAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL17486819 | 0.85 | FGFR1 (0.73) | FGFR1MAPTSMN1; SMN2ALDH1A1GABRP | |
| SCHEMBL16387135 | 0.84 | FGFR1 (0.63) | FGFR1MAPTSMN1; SMN2ALDH1A1GABRP | |
| SCHEMBL7986978 | 0.83 | FGFR1 (1.00) | FGFR1HTT | |
| SCHEMBL19848456 | 0.82 | FGFR1 (0.73) | FGFR1MAPTSMN1; SMN2ALDH1A1GABRP | |
| Hydrochloric Acid SCHEMBL7975764 | 0.82 | FGFR1 (0.97) | FGFR1HTT | |
| SCHEMBL20603969 | 0.82 | DHFR (0.60) | FGFR1MAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL19350794 | 0.81 | FGFR1 (0.62) | FGFR1MAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL38651826 | 0.81 | FGFR1 (0.62) | FGFR1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424924-B1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) | 2023-05-24 | — | — | EP | disclosed |
| CN-109071523-B | Urea compound, preparation method and medical application thereof | 恩瑞生物医药科技（上海）有限公司 | 2022-05-31 | — | — | CN | disclosed |