Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206097 | 0.83 | MMP8 (0.50) | MMP8GAATDP1SMN1; SMN2AMPD2 | |
| SCHEMBL11343521 | 0.83 | CYP2C19 (0.46) | CYP2C19SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL23688603 | 0.82 | CYP2C19 (0.65) | CYP2C19MMP8GAASMN1; SMN2MAPT | |
| SCHEMBL8669701 | 0.82 | CYP2C19 (0.65) | CYP2C19MMP8GAASMN1; SMN2MAPT | |
| SCHEMBL23688606 | 0.82 | CYP2C19 (0.65) | CYP2C19MMP8GAASMN1; SMN2MAPT | |
| SCHEMBL9000765 | 0.82 | MMP8 (0.49) | MMP8GAATDP1SMN1; SMN2LMNA | |
| SCHEMBL8818975 | 0.81 | MMP8 (0.48) | MMP8GAATDP1SMN1; SMN2LMNA | |
| SCHEMBL27608413 | 0.81 | MMP8 (0.48) | MMP8GAATDP1SMN1; SMN2AMPD2 | |
| SCHEMBL4886826 | 0.81 | MMP8 (0.48) | MMP8GAATDP1SMN1; SMN2LMNA | |
| SCHEMBL27587299 | 0.81 | MMP8 (0.48) | MMP8GAATDP1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113583020-B | JAK2 inhibitor and application | 百极弘烨（广东）医药科技有限公司 | 2022-04-22 | — | — | CN | disclosed |