SCHEMBL296242

SCHEMBL296242

COC(=O)C(Br)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20612847 1.00
SCHEMBL30412316 1.00
SCHEMBL6669714 0.89 ZDHHC7 (0.44)
SCHEMBL1415237 0.81 ZDHHC7 (0.65)
SCHEMBL1415280 0.81 ZDHHC7 (0.54)
SCHEMBL5965786 0.81 ZDHHC7 (0.65)
SCHEMBL23795547 0.80
SCHEMBL1107132 0.80
SCHEMBL11740013 0.80 ZDHHC7 (0.44)
SCHEMBL343724 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959993-B Synthesis method of 2-aryl propionic acid compound 山东中医药大学 2025-01-07 CN claimed
CN-118994091-A Quinone diterpene acene vinyl alcohol ester adduct, preparation method and melanoma treatment application 中国医学科学院药物研究所 2024-11-22 CN claimed
CN-117209394-A Preparation method of diacetone acrylamide 潍坊科麦化工有限公司 2023-12-12 CN claimed
CN-115959993-A Synthetic method of 2-aryl propionic acid compound 山东中医药大学 2023-04-14 CN claimed
CN-104058991-B Novel Process For The Preparation Of Amino Acid Derivatives 优时比制药有限公司 2017-04-12 CN claimed
CN-106090824-A A kind of photosensitive stealthy art lantern 陕西理工学院 2016-11-09 CN claimed
US-8946476-B2 Process for the preparation of amino acid derivatives UCB PHARMA GMBH (DE) 2015-02-03 US claimed
CN-104058991-A Novel Process For The Preparation Of Amino Acid Derivatives UCB PHARMA SA 2014-09-24 CN claimed
CN-102209707-B Novel process for producing amino acid derivative UCB PHARMA SA 2014-07-09 CN claimed
EP-2352721-B1 NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA GMBH (DE) 2013-03-27 EP claimed
US-20110263899-A1 Novel Process for the Preparation of Amino Acid Derivatives UCB PHARMA GMBH (DE) 2011-10-27 US claimed
CN-102209707-A Novel process for producing amino acid derivative UCB PHARMA SA 2011-10-05 CN claimed
EP-2352721-A1 NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB Pharma GmbH (DE) 2011-08-10 EP claimed
WO-2010052011-A1 NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES UCB PHARMA, S.A. (BE) 2010-05-14 WO claimed
CN-1083451-C Process for synthesizing doxazosin mesylate GUANGDONG KANGMEI HARMACEUTICA (CN) 2002-04-24 CN claimed
EP-0894796-B1 Imidazolines substituted with a heterocyclic ring as alpha-2 antagonists ADIR (FR) 2001-06-06 EP claimed
CN-117659017-B TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof 北京华益健康药物研究中心 2026-05-15 CN disclosed
US-12570620-B2 Covalent inhibitors of creatine kinase (CK) and uses thereof for treating and preventing cancer DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-03-10 US disclosed
US-4017512-A Process for producing N-alkylhydroxylamines SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-04-12 US disclosed
US-3975365-A Inhibitory octapeptides angiotensin II G. D. SEARLE & CO. (US) 1976-08-17 US disclosed