Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035983 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3MAPTELANE | |
| SCHEMBL18987136 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3MAPTELANE | |
| SCHEMBL4035987 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3MAPTELANE | |
| SCHEMBL29261319 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1CHRM3MAPTELANE | |
| SCHEMBL29261316 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1CHRM3MAPTELANE | |
| SCHEMBL29261317 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1CHRM3MAPTELANE | |
| SCHEMBL3378115 | 0.85 | CHRM2 (0.40) | CHRM2CHRM1CHRM3MAPTNPC1 | |
| SCHEMBL14141084 | 0.85 | CHRM2 (0.40) | CHRM2CHRM1CHRM3MAPTNPC1 | |
| SCHEMBL27378721 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1CHRM3MAPTELANE | |
| SCHEMBL31080746 | 0.80 | CHRM2 (0.36) | CHRM2CHRM1CHRM3MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688156-A1 | LACTAM-CONTAINING IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201322-A1 | LACTAM-CONTAINING IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-03 | — | — | WO | disclosed |
| CN-114405547-A | Metal complexes | 利兹大学 | 2022-04-29 | — | — | CN | disclosed |