SCHEMBL29624641

SCHEMBL29624641

O=C(O)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15792447 1.00 THRB (0.50) THRBCA1CA2MMP1MMP2
SCHEMBL15792712 1.00 THRB (0.50) THRBCA1CA2MMP1MMP2
Ammonia Solution, Strong SCHEMBL30538863 0.98 THRB (0.48) THRB
Ammonia Solution, Strong SCHEMBL30602804 0.98 THRB (0.48) THRB
SCHEMBL9137249 0.98 THRB (0.46) THRB
SCHEMBL7263134 0.96 THRB (0.46) THRB
Ammonia Solution, Strong SCHEMBL29598744 0.95 THRB (0.44) THRB
SCHEMBL915267 0.93 THRB (0.43) THRB
SCHEMBL917716 0.93 THRB (0.43) THRB
Ammonia Solution, Strong SCHEMBL29408591 0.91 THRB (0.41) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114405547-A Metal complexes 利兹大学 2022-04-29 CN disclosed