Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | ILK | Q13418 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21482756 | 1.00 | MAP4K1 (0.41) | MAP4K1NPSR1KDM4EALDH1A1HPGD | |
| SCHEMBL21486348 | 0.86 | MAP4K1 (0.42) | MAP4K1ALDH1A1MAPTTDP1ADORA2A | |
| SCHEMBL20209580 | 0.83 | MAP4K1 (0.35) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL20208919 | 0.79 | MAP4K1 (0.36) | MAP4K1ADORA2AADORA1VCP | |
| SCHEMBL20187673 | 0.73 | NPSR1 (0.42) | NPSR1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL17090692 | 0.71 | ADORA2A (0.38) | MAP4K1NPSR1KDM4EALDH1A1HPGD | |
| SCHEMBL29977899 | 0.70 | NPSR1 (0.56) | NPSR1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL16418573 | 0.70 | NPSR1 (0.56) | NPSR1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL13072745 | 0.69 | ADORA2A (0.37) | MAP4K1KDM4EALDH1A1HPGDATM | |
| SCHEMBL27388937 | 0.69 | MAP4K1 (0.48) | MAP4K1NPSR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214141-B | Benzodiazolium compounds as ENaC inhibitors | 企业治疗学有限公司 | 2022-05-31 | — | — | CN | disclosed |